Sr. Manager, Biomarker Data Scientist

Key Skills

Aartificial intelligence, Data science techniques, Data Visualization, Deep Learning, Machine learning techniques, Optimization, Planning and organization, Python Programming, R Programming, SAP, SQL, Translation

Job Description

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

Senior Manager – Biomarker Data Scientist

This is a new position. You will join a new cutting-edge Drug Development Data Science and Biomarker team to advance the global drug development process. We are looking for candidates with strong computational, statistical, and biological capabilities with a demonstrated track record of translating complex data into testable hypotheses and experience modeling multimodal (clinical, omics, real-world data) using the classical ML and Deep Learning algorithms. We are looking for hands-on state-of-the-art practitioners. 

What you’ll do:

• Develop and apply novel or existing computational methods for patient segmentation from multimodal clinical and omics datasets for various treatment modalities in partnership with Translational, Clinical and Statistical Scientists
• Partner with lead and protocol statisticians in writing, reviewing and executing protocols and statistical analysis plans (SAP) for biomarkers and diagnostics, highlighting the biomarker strategy for clinical drug development
• Execute biomarker analyses on datasets from BMS clinical trials and real-world data cohorts
• Perform relevant and innovative statistical analyses of high-dimensional (e.g. gene expression, sequencing) data generated by cutting edge technologies
• Execute and contribute to the scientific and statistical strategy of drug development, including development of predictive biomarker(s) and precision medicine
• Optimize and validate biomarker assays for clinical trial usage.

• Develop, implement, and apply state-of-the-art algorithms to address key business problems and drive the implementation of innovative statistical methods in support of biomarker strategy

• Formulate, implement, test, and validate predictive models and implement efficient automated processes for producing modeling results at scale.
• Responsible for collaborating with cross-functional teams, including but not limited to clinicians, data scientists, translational medicine scientists, statisticians, and IT professionals.
• Manage and coordinate resources to produce quality deliverables within timelines for competing priorities.

Key Requirements:

• Ph.D. in a relevant quantitative field (i.e. Computational Biology, Biostatistics, Statistics, Computer Science, etc.) and 1+ years of academic/industry experience or Master’s Degree in a relevant quantitative field and 3+ years of industry experience
• Strong experience in the analysis of data generated by one or more -omics or molecular assays is required
• Knowledge of molecular biology, understanding of disease pathways are preferred
• Strong experience in biomarker data analysis with data generated from clinical trials, or electronic health records 
• Experience in modeling methods particularly in their application to pharma R&D Experience in the application of AI/ML, and proficient in SQL, Python, and R and cloud platforms
• Experience developing statistical and machine learning models on high dimensional and high throughput data for time to event data and longitudinal outcomes 
• Perspective in leveraging innovative approaches to expedite drug development and address the complexities of emerging data
• Ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects.
• Strong problem-solving and collaboration skills, and rigorous and creative thinking.
• Excellent communication, data presentation, and visualization skills.
• Capable of establishing strong working relationships across the organization