Scientific Director, Reverse Translational​

Key Skills

Aartificial intelligence, Agile methodologies, Data Analysis, Data Mining, Data Visualization, Effective communication skills, Machine learning techniques, Presentation skills

Job Description

We are seeking a highly motivated and talented Scientific Director to join our Infectious Disease team in Pennsylvania, Belgium, or Stevenage. In this role, you will be responsible for providing scientific expertise and strategic guidance in the field of Hepatitis B Virus (HBV) research, with a focus on reverse translation. The Scientific Director will collaborate with cross-functional teams to drive the discovery and development of innovative therapies for HBV. The successful candidate will play a critical role in advancing GSK's HBV Cure portfolio and contributing to the global effort to combat HBV infection. Working in collaboration with a cross-functional biomarker, clinical, computational biology, AI/ML team, you would lead data analysis strategies and embed reverse translation capabilities to expand further our understanding of disease types, treatment response and deliver novel targets.

Key Responsibilities:

• Scientific Strategy Development: Develop and implement a scientific strategy for HBV research, with a specific focus on reverse translation. Stay updated with the latest scientific advancements, emerging technologies, and therapeutic approaches in the field of HBV.
• Reverse Translation Expertise: Possess deep knowledge and expertise in complex data mining, data analysis, data visualization with a preference to infectious diseases and immunology, including understanding of viral replication, host-virus interactions, disease mechanisms, and therapeutic targets. Leverage internal, external, and real world evidence data sets to support hypothesis testing and generate novel insights. 
• Team Leadership: Collaborate across a matrix environment to enable optimized data ingestion and analysis processes to enable discoveries and build disease area focused datasets.
• Cross-functional Collaboration: Collaborate closely with cross-functional teams including Genomic Sciences, Clinical Biomarker, Clinical Development, and AI/ML to drive the discovery and development of novel therapies for HBV. Provide scientific input and support to project teams and contribute to the overall HBV portfolio strategy.
• External Collaboration: Establish and maintain collaborations with external academic institutions, research organizations, and key opinion leaders in the field of HBV. Foster strong relationships and partnerships to enhance GSK's scientific capabilities and access to cutting-edge research.
• Scientific Communication: Effectively communicate scientific findings, research progress, and strategic insights to internal stakeholders, senior management, and external scientific communities. Present research findings at scientific conferences, symposiums, and advisory boards to enhance GSK's scientific reputation.
• Innovation and Research Excellence: Drive innovation and research excellence in HBV reverse translation through the application of novel technologies, methodologies, and scientific approaches. Identify and evaluate new research opportunities and emerging trends in the field.
• Compliance and Ethics: Adhere to GSK's policies and guidelines, including the Code of Conduct, Research Ethics, and Intellectual Property policies. Ensure all research activities and collaborations are conducted in an ethical and compliant manner.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• PhD in a scientific discipline (e.g., Virology, Immunology, or Systems Biology) with a focus on HBV research.
• 10+ years of experience in the pharmaceutical or biotechnology industry, with a strong understanding of reverse translation and infectious diseases, preferably with hepatitis virus.
• Experience in leading and managing scientific teams, fostering a collaborative and inclusive work environment.

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Proven track record of high-impact contributions to translation and biomarker data analysis and discovery of novel results and data analysis approaches.
• Extensive knowledge of HBV virology, host-immune to virus interactions, and therapeutic approaches.
• Excellent communication and presentation skills, with the ability to effectively convey complex scientific concepts to diverse audiences.
• Strong publication record in peer-reviewed scientific journals and active participation in scientific conferences and forums.
• Familiarity with clinical biomarker analyses, regulatory requirements and drug development processes. 

Why GSK?

We’re combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.

In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention.