Senior Scientist - Psychiatry

Key Skills

Analytical and Problem solving, Biomedical Imaging, Data science techniques, Design, Genomic data, Presentation skills, Project management, Translation

Job Description

We are inviting applications for senior scientists who are working to develop human cell-based models of neuropsychiatric and neurodegenerative disorders. We seek biomedical engineers, bioengineers, developmental biologists and molecular and cellular biologists who apply state-of-the-art approaches to cellular engineering and perform advanced screening and disease modeling for therapeutic discovery. The successful candidate will develop methods to differentiate induced pluripotent stem cells (iPSCs) to produce brain cells (e.g. neurons, microglia) and cerebral organoids for functional characterization of molecularly defined markers of neuropsychiatric and neurodegenerative disease, including Schizophrenia, Bipolar disorder and Alzheimer’s disease. The development of human disease models will allow CDN members to resolve the interactions between genetic variants, cell types and molecular functions in an enhanced disease-relevant context.

The Center for Disease Neurogenomics provides a hub for neurogenomics and disease biology geared towards developing and enhancing precision medicine across neuropsychiatric disorders. The candidates will join an outstanding team of scientists with world class expertise in a broad range of disciplines, including genetics and genomics, neuroscience and clinical psychiatry. CDN promotes collaboration, inclusion, and cross-disciplinary interactions between basic wet lab and dry lab scientists and clinicians, and provides strong support to junior scientists.

Responsibilities:

• In addition to possessing independent problem solving skills and a desire to explore and implement emerging methodologies, the successful applicant will establish new research protocols and procedures, interpret results, provide feedback to guide experimental design or project focus and prepare results for presentation, publication and funding applications. 

About the Center for Disease Neurogenomics

• The Center for Disease Neurogenomics is part of the Mount Sinai Health Care System, which is one of largest hospital systems in the United States, and the Icahn School of Medicine, which houses over 5000 faculty in outstanding departments in psychiatry, neuroscience, genetics, immunology, stem cell biology, and experimental therapeutics. The highly integrated structure of Mount Sinai’s departments, institutes and clinical divisions provide a unique environment for scientific and medical collaborations that foster an ideal atmosphere for innovations aimed at addressing 21st century biomedical challenges. Mount Sinai is ranked as one of the nation’s top biomedical institutions in research, patient care, and education, and over the last 10 years has become a leader in biomedical data science. 

About the Department of Psychiatry at ISMMS

• The Department of Psychiatry at Mount Sinai is a vibrant community of clinicians, researchers, educators, and trainees committed to discovering the causes of and treatments for mental and emotional disorders. We are ranked among the nation’s top psychiatry departments for funding from the National Institutes of Health.

About the Friedman Brain Institute at ISMMS

• The Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai is one of the world’s premier institutions dedicated to advancing our understanding of brain and spinal cord disorders, and driving innovative approaches to new treatments and diagnostic tests through translational research. We are committed to the best in education, research, and clinical care.

About the Icahn School of Medicine at Mount Sinai

• The ISMMS is an international leader in medical and scientific training, biomedical research, and patient care. It is the medical school for the Mount Sinai Health System, which includes seven hospital campuses, and has more than 5,000 faculty and nearly 2,000 students, residents and fellows. Our unwavering pursuit of intellectual exchange, breakthrough research, and multidisciplinary teamwork propels us ever forward in biomedical discoveries and advances. We pursue ideas that often challenge conventional wisdom to revolutionize the practice of medicine and produce dramatically better outcomes for patients.

Apply:

To be considered for a position in the Roussos Laboratory, please submit a cover letter, CV and contact details for at least 3 referees to panagiotis.roussos (at) mssm.edu.

The Icahn School of Medicine at Mount Sinai is an Equal Opportunity and Affirmative Action Educational Institution and Employer. Women and members of underrepresented minority groups are strongly encouraged to apply. In addition, candidates are encouraged to use the cover letter to provide any additional information the candidate feels relevant to disadvantaged backgrounds.

Requirements:

• Qualifications and required skills:

  Ph.D. degree in biomedical engineering, bioengineering, developmental biology, molecular and cellular biology, or related discipline with expertise in iPSCs.

  Strong motivation, good communication skills and the ability to work independently.

Strength Through Diversity

The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by: