Laboratory Supervisor-Personalized Med

Mount Sinai Health System
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Job Description

The Charles Bronfman Institute for Personalized Medicine (CBIPM) brings together a group of experts in the clinical and biological data sciences committed to exploring the nature of human disease through cohort studies. We carry out these studies at scale in clinics, emergency rooms, and inpatient units within the Mount Sinai Health System. 

The institute collaboratively and rapidly translates key discoveries into experimental interventions and new standards of care. We aim to position Mount Sinai at the forefront of data-driven clinical care by creating a landscape where every patient can be a research participant, clinical decisions are data-driven, and care is continuously optimized. 

Duties and Responsibilities: 

Research Laboratory Supervisor, Charney Lab, Icahn School of Medicine at Mount Sinai, New York City. The Research Laboratory Supervisor will lead efforts to oversee research projects and support collaborations within CBIPM within the laboratory of Alexander Charney, MD, PhD, Co-Director, CBIPM, Associate Professor, Genetics and Genomic Sciences, Psychiatry, Neuroscience, and Neurosurgery. Reporting directly to the Laboratory Manager for CBIPM, the Research Laboratory Supervisor will be responsible for the Charney lab project portfolio which includes several complex and multi-faceted efforts, including multiple NIH-funded programs. The incumbent will be responsible for fully supporting the development and execution of research strategies in collaboration with key team members and will play a key role in fostering the growth of the research program and contributing to new science. 

The ideal candidate will have the following skills and experience:

  • Professional experience working at the bench in a scientific laboratory with a deep understanding of the following techniques:

Fibroblast Tissue Culture

Generating CRISPR experiments

QA/QC of DNA or RNA samples using qubit, nanodrop, or bioanalyzer systems

Large sample quantity management and tracking

Tracking and storing samples using LIMS

10x Single-Cell GEM Generation and Library Preparation

DNA and RNA extraction

Processing CPT, SST, and Tempus blood vacutainers

Genotype Validation using Sanger Sequencing

  • Organized with steadfast attention to detail, passion for science
  • Effective communication and interpersonal skills; able to establish good working relationships and collaborate with networks of employees of all backgrounds
  • Demonstrated credibility: diplomatic, decisive, straightforward, honest
  • Willingness to commit to this position for the long-term. 

Primary responsibilities include: 

  • Support the Charney Lab and its collaborations with third parties by coordinating activities to achieve project goals.
  • Coordinate research activities within the wet lab, including holding regular meetings, managing samples and data between, and liaising with team members and collaborators at multiple institutions.
  • Oversee biospecimen processing, database work, and other research processes.
  • Track and report project activities and costs to leadership.
  • Oversee, manage, and train research associates in biospecimen processing and other experimental work.
  • Develop new wet lab techniques to be implemented such as ATAC-seq or Hi-C as needed.
  • Ensure all personnel follow fire safety and environmental health and safety standards.
  • Perform other duties as requested. 

Qualifications: 

  • Preferred:

Graduate degree in science

2+ years of academic job experience

Job or research experience in data science and/or genomics

  • Required:

Bachelor’s degree in life sciences or related field.

Basic laboratory skills.

Proficiency in Microsoft Office Suite.

Demonstrated ability to work effectively, communicate clearly, and accomplish goals.

Pristine attention to detail and ability to manage time appropriately, able to multitask in a fast-paced environment.

Effective interpersonal skills, able to establish good working relationships and collaborate with networks of employees at all levels, able to foster cooperation in others. 

Company Info.

Mount Sinai Health System

The Mount Sinai Health System is a hospital network in New York City. It was formed in September 2013 by merging the operations of Continuum Health Partners and the Mount Sinai Medical Center. The Health System includes more than 6,600 primary and specialty care physicians and 13 ambulatory surgical centers. It has ambulatory practices throughout the five boroughs of New York City, Westchester County, and Long Island, along with more than 30 aff

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