Pharmacometricians_3 years temporary contract

Key Skills

Deep Learning, Machine learning techniques, MATLAB Programming, Planning and organization, R Programming, SAS

Job Description

Your Responsibilities include:

• Develop and execute scientifically sound, innovative and business-oriented Modeling & Simulation (M&S) strategic plans for projects in various disease areas and different stages of product development, including regulatory submissions.
• Develop and execute appropriate (population) pharmacokinetic and (population) pharmacodynamic models for the project and apply, if available for the project, empirical and/or mechanistically-based drug disease models.
• Conduct simulations to inform drug development decisions such as dosage regimen selection and other trial design features.
• Communicate the outcome of M&S analysis to the project teams to support efficient discussion and decision making.
• Contribute to responses to health authority requests and interactions to align on Clinical development and M&S strategy
• Interact on a scientific level with partners in project team(s) with regards to all aspects of the application of M&S to ensure efficient and appropriate integration of M&S strategy and results into internal and external project documents (e.g. Clinical Development Plan, Investigator Brochure, NDA documents)

Your profile

• MD, PharmD or PhD (in natural sciences, mathematics, physical sciences or engineering or any combination of these) with at least 3-5 years experience* in planning and conducting M&S projects for clinical study data in a pharmaceutical industry setting. 
• Strategic mindset and understanding of how and when M&S can contribute value in drug development and support decision making.
• Significant experience with M&S software (e.g. NONMEM, Monolix, Phoenix, MATLAB, Gastroplus, Simcyp, SAS, R,…)
• Knowledge in technological advances like bayesian modelling and artificial intelligence (e.g. machine and deep learning) is desired as well as a keen interest for deep understanding of disease biology.
• Ability to influence and lead without authority in a network organization
• You exhibit a growth mindset. You ask for feedback and act on it. You embrace opportunities to gain new skills and perspectives and provide honest feedback to others to help them grow.
• You are able to follow the science. You act on facts and data, not opinions and go where the science and the unmet needs of patients lead you.
• Efficient written and oral communication.
• You are able to radically simplify and prioritize for impact. You invest your time in things that accelerate progress for patients. You stop doing things that do not.

* The seniority level of the position will be determined based on the experience of the successful candidate

Your location

This position is located in Basel or in Welwyn.

You’re someone who wants to influence your own development. You are looking for a company where you receive the opportunity to pursue your interests across functions and geographies. Working in a multi-cultural environment motivates you. 

Are you ready to apply? We want someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche.

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.