Senior Scientist, Machine Learning

Key Skills

Effective communication skills, Machine learning techniques, NumPy, Pandas, Python Programming, PyTorch, SciPy, Writing

Job Description

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way.

What this position is all about: Cellarity is seeking a highly motivated Senior Scientist, Machine Learning with deep expertise in next-generation-sequencing (NGS), single-cell genomics, and development of Computational Biology (CB) and Deep Learning (DL) approaches. You will be responsible for developing pipelines to accurately analyze drug perturbational datasets, supporting drug prediction and scientific publication activities, and developing analytical tools that prioritize compounds that revert disease cellular state. You will work closely with the Machine Learning, Computational Biology, and Scientific Projects teams and collaborate cross-functionally within Cellarity to advance drug discovery programs. The ideal candidate must be results oriented and have excellent communication skills and be willing to work in a highly dynamic and fast-paced entrepreneurial environment.

What you would be responsible for:

• Support scientific publications to further advance Cellarity’s reputation.
• Develop best data practices to enable robust model development from omics datasets.
• Leverage single-cell and computational biology techniques to support the expansion of drug perturbational datasets and identification of drug candidates.
• Develop and maintain DL and ML predictive models that are core to identification of compounds modulating disease states.
• Collaborate with scientists from Biology, Technology, and Chemistry teams as part of the wider drug discovery project team.

What experiences will you need:

• Doctoral Degree in Computational Biology, Machine Learning, Statistics, Computer Science, and related disciplines, with a minimum of 5 years of industry experience.
• Extensive experience in developing best data practices for bulk and single-cell NGS data.
• Extensive experience in developing and maintaining DL and ML models for biological applications.
• Extensive experience in Python, sklearn, pandas, numpy, and pytorch/TF.
• Knowledge of pathway enrichment, differential expression analysis, and cell type annotation.
• Ability to successfully work in cross-functional teams with an emphasis on collaboration and communication across the department.
• Ability to successfully work in cross-functional teams with an emphasis on collaboration and communication across the department.

What sets you apart:

• Industry experience, with emphasis on drug discovery projects.
• Industry experience, with emphasis on drug discovery projects.
• Demonstrated mastery of modern computational analysis of NGS datasets and development of novel DL workflows.
• A passion for deriving novel scientific trajectories that break the boundaries of common drug discovery approaches.
• Strong oral and written communication skills, collaboration, and time-management skills.

What it’s like to work at Cellarity

At Cellarity, we

• Push Boundaries: We create a legacy with breakthrough science in service of patients.
• Inject Energy: We build strengths from different perspectives and tell it like it is
• Own it: We transcend our job descriptions and relentlessly follow through on our commitments.
• Go all out: We work quickly and with conviction.

Company Summary: Cellarity’s mission is to fundamentally redesign the way drugs are created for the sake of bringing new hope to patients. By shifting the focus from a single target to the underlying cellular dysfunction, we unravel the complexity of disease biology and create medicines that were never before possible. The company has developed unique capabilities that link biology and chemistry with high dimensional-omics data from which we design medicines against the cellular signature of disease. The Cellarity platform allows us to uncover new biology in diseases even in the absence of known causal targets. The company has drug discovery programs underway in several disease areas, including metabolic disease, hematology, and immunology. Cellarity recently completed a Series C financing, and has raised a total of $274M from all funding rounds to date, with contributions from world-renowned investors alongside Flagship Pioneering who created the company. Cellarity’s goal is to grow into a fully integrated next generation Biotech company driving a new age in drug creation.

Cellarity is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Cellarity does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Cellarity or its employees is strictly prohibited unless contacted directly by Cellarity’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Cellarity, and Cellarity will not owe any referral or other fees with respect thereto.