Postdoctoral Fellow – Machine Learning/Genome Mutability & Organization/Molecular Interactions

Moffitt Cancer Center
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Job Description

At Moffitt Cancer Center, we come face-to-face with cancer every day, but we also see courage. And it inspires us to be the safest and best place for cancer care – to bring greater hope to every patient we serve. It’s why we’ve been continually named One of the Top Places to Work in the Tampa Bay Area. As the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, Moffitt employs some of the best and brightest minds from around the world. Moffitt is the leading cancer hospital in both Florida and the Southeast and has been nationally ranked by U.S. News & World Report since 1999. Because working at Moffitt is both a career and a mission: to contribute to the prevention and cure of cancer. Join a dedicated, diverse and inclusive team of over 7,000 to be a part of the Courageous future we envision.


We seek a creative and motivated postdoctoral researcher with background in molecular interactions and machine learning to join the team of Dr. Aleksandra Karolak. Our current projects focus on applications and development of AI to study structure and interactions of biomolecules, DNA and proteins mutations, and design of novel therapeutics. If your background overlaps and if you are interested in understanding e.g., impact of DNA damage on responses to treatment, genome conformation or protein mutations, or identification of novel compounds to treat cancer – we encourage you to apply. We have exciting opportunities for you within our team at the institution that will strongly support your scientific growth and future successes.

The Molecular AI Group in the Machine Learning Department at Moffitt combines multidisciplinary and multiscale approaches from the fields of chemistry, biology, machine learning, information theory, and mathematical oncology, to advance cancer research. We collaborate with the departments of gastrointestinal oncology and molecular medicine/drug discovery. We also actively collaborate with the extramural oncology centers and academic institutions.

Position Highlights:

  • Moffitt integrates excellent patient care with cutting-edge clinical and basic research. Having a cancer hospital on-site provides unique opportunities for translational research.
  • The position is essential for development of comprehensive tools benefiting basic to clinical research through 1) identification of novel approaches and biomarkers to treat cancer, and 2) through the improved stratification of cancer patients.
  • The position offers vibrant and interactive work environment in the Quantitative Science Division and results will bring value beyond the community of Moffitt patients.
  • Outstanding mentorship from expert faculty with wide-ranging funded research programs including T32 Training Grants.
  • You will be encouraged and supported to apply for training grants.

The Ideal Candidate:

  • High motivation and desire to be part of multidisciplinary group, good work ethics.
  • Excellent interpersonal and communication skills (written and verbal).
  • Documented experience with machine learning concepts, tools, and applications.
  • High proficiency with at least one of the programming languages and statistical packages.
  • Deep knowledge and documented expierence with processing of biological data sources and databases (e.g., various omics data, drug libraries)
  • Documented experience with concepts underlying structure, folding, interactions between proteins, DNA, and/or small molecules.
  • Preferable experience in modeling of biomolecules, AI-enabled interaction networks, and AI-aided drug design.
  • Preferable knowledge of cancer biology.
  • Experience with extraction, handling, and processing of large data sets.


  • Data preparation, organization, and analysis.
  • Development of new and tuning of existing models and analytical approaches.
  • Presentation of data and results in a clear and concise manner.
  • Active participation in the group meetings and meetings with the collaborating teams.
  • Ability to work with the team and independently.
  • Supervision of undergraduate and graduate students.
  • Preparation of grant applications, publications, and presentations.
  • Meeting project goals.

Credentials and Qualifications:

  • Ph.D. degree and research experience in the fields of machine learning, computer science in biomedical applications or related field of study.
  • At least one first-author publication.

Interested applicants should submit a current CV with recent publications, a cover letter summarizing their research training and accomplishments, and contact information for three references.

Moffitt Postdocs are provided with Medical (Moffitt covers premium for team member) effective upon start date and eligible for Dental, Vision, Paid Time Off, Retirement, Parental Leave and more. You may be eligible for relocation assitance per policy. Reason to relocate, Tampa is a thriving metropolitan city that provides its residents a high quality of life. The Tampa Bay area has become a hub for ground-breaking research, welcoming individuals from around the globe. This diverse city is engulfed with rich culture, year-round activities for all, beautiful beaches, amazing cuisine and so much more.

Company Info.

Moffitt Cancer Center

Houston Lee Moffitt Cancer Center & Research Institute is a nonprofit cancer treatment and research center located in Tampa, Florida. Established in 1981 by the Florida Legislature, the hospital opened in October 1986 on the University of South Florida's campus. Moffitt is one of two National Cancer Institute-designated Comprehensive Cancer Centers based in Florida.

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