Senior Bioinformatics Scientist

Key Skills

Algorithms, Animal agriculture optimization , Business Development, Cloud computing, Computational Algorithms, Descriptive analysis , Effective communication skills, Forensic Medicine, HIPAA, Molecular biology, Novel algorithms, Oil Technology , Planning and organization, Python Programming, R Programming, RJ Metrics, SQL Server, Statistical modeling, Statistics

Job Description

Invitae is a biotechnology company focused on providing tools and services for clinical research applications of genomics. Our mission is to unlock the power of precision medicine in improving patient care by providing a technology platform to advance genomics and facilitate collaborative research.

Invitae is seeking senior Bioinformaticians to join our team. This role will be centered around crafting tools and algorithms to complement assay/product development.We are looking for someone who is able to perceive a problem clearly and dissect it into components which can be resolved programmatically. Having a comprehensive grasp of genomics and next generation sequencing will be key to succeeding in this role. The candidate should be independent, well organized and collaborative with clear communication skills. In addition, ability to frequently switch between tasks will be helpful.

As vital, but not as a primary role, the Senior Bioinformatics Scientist will assist the Clinical team in ad-hoc analysis and research required to meet regulatory requirements. You will be responsible for scaling our pipelines as we work toward our goal of providing low-cost genetic answers to billions of people.

Responsibilities:

• Build and evaluate algorithms and statistical models to improve existing genetics applications within and beyond NGS technologies and build novel ones
• Drive genetics technology development in a cross-disciplinary setting by critically analyzing and deriving insights from experimental data (including NGS, arrays, and novel technologies) using open source NGS tools and building custom tools when needed
• Working with wet lab scientists to independently design experiments and communicate conclusions for internal review
• Develop reproducible analysis for research and development purposes
• Help draft and implement the data analysis for clinical software/assay validations
• Develop standard processes for analysis of NGS data including optimization of parameters, and consensus approaches across various tools
• Maintain a visible profile in the Bioinformatics community through publications, conference presentations, and collaborations
• Review, understand, and stay in compliance with Invitae HIPAA Security policies and procedures

Qualifications:

• MS with 8+ years experience or PhD with 5+ years experience in Bioinformatics or Computational Biology
• Proficient in R/Python, *nix, and SQL for data analysis
• Good understanding of standard bioinformatic tools used in NGS pipelines
• Proven understanding of pipeline workflow engines: Nextflow, Snakemake
• Strong knowledge of Genomics and Molecular Biology
• Solid understanding of Illumina sequencing technologies and metrics
• Formal statistics background is a plus
• Software development experience (preferred)
• Understanding of Cloud Computing (preferred)

At Invitae, you’ll work alongside some of the world’s experts in genetics and healthcare at the forefront of genetic medicine. Our teams thrive in our dynamic organization, which has been designed to empower them to make the biggest impact they can for our patients. We give our employees the ability to explore interests and capabilities broadly within the organization. We prize freedom with accountability and offer significant flexibility. We also provide excellent benefits and competitive pay in a fast-growing organization.

At Invitae, we’re changing healthcare to change lives. Join us.