Intern, Biology Discovery

Key Skills

Unix Operating system, Java Programming, Python Programming, C++, Git, AWS, Cloud computing, MATLAB Programming, Docker, Shell Scripting language, Linux Operating system, R-Shiny, Github, SAS, Containerization, Tidyverse

Job Description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

The Opportunity

Denali is seeking a motivated graduate student for an internship position in the Biology Discovery group to gain meaningful research experience in blood-brain barrier and CNS disease biology. This is a hands-on laboratory position with abundant opportunity for collaboration with other researchers in a dynamic and fast-paced environment. The ideal candidate will have a strong desire to learn new research techniques and apply these methods to support therapeutic and exploratory projects.

Responsibilities

• Work under supervision of Denali scientists to design and conduct experiments to elucidate responses of targeted therapeutics in mouse models of Alzheimer’s disease and understand large molecule transport in the CNS
• Perform hands-on experiments (such as immunohistochemistry, microscopy, ELISA, western blot, RNA extraction, and more)
• Generate, analyze, and interpret data, including documentation in an electronic lab notebook
• Present work to Denali project and function teams

Requirements

• Candidates pursuing a MS/PhD in neuroscience or related field
• Previous experience in a research lab, either through previous internships or research fellowship, with immunohistochemistry, microscopy, and western blotting experience preferred
• Motivated, proactive, and organized with strong communication skills and ability to work in a highly collaborative environment
• Proficiency in Microsoft Office applications

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state or local protected class.

Job Facts:

• Start Date: Summer 2023
• Length of Assignment: 10 - 12 weeks
• Location: South San Francisco, CA
• Job Type: Paid Internship