Intern, Biostatistician

Key Skills

AWS, C++, Cloud computing, Containerization, Docker, Git, Github, Java Programming, Linux Operating system, MATLAB Programming, Python Programming, R-Shiny, SAS, Shell Scripting language, Tidyverse, Unix Operating system

Job Description

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

The Opportunity

Denali is seeking a highly motivated individual with strong statistical methodology knowledge, R programming expertise and problem-solving skills to join us for a summer Biostatistician internship in the Biometrics group at Denali Therapeutics. The successful candidate will support impactful projects related to reviewing literature, analyzing real-world data, developing new statistical methodologies and running simulations with guidance from a mentor. The intern will gain an in-depth understanding of drug development, experience working in a fast-moving industry environment, and subject domain knowledge in the field of neurodegeneration.

Responsibilities

• Support topics related to but not limited to key study design and analysis of clinical trials, analysis of biomarker data, or development of statistical methodology
• Research and apply appropriate statistical methods as well as evaluate the advantages and disadvantages of the various methods via simulation.
• Document statistical models and create maintainable/reproducible code for data analyses to be shareable within the department.
• Present the results at cross-functional and departmental meetings at the conclusion of the internship. 

Requirements

• Currently enrolled or recent graduate in a PhD program in Biostatistics, Statistics, Mathematics, or related science discipline.
• Strong interest in biotech/pharma, clinical trials and drug development.
• Proficiency with using R (tidyverse, Rmarkdown, ggplot2) and GitHub to create operational, robust, well-documented code; familiarity with creating interactive web apps (R Shiny, plotly dashboard, htmlwidgets) and AWS S3 is a plus. 
• Experience with simulations.
• Excellent oral, written, and presentation skills.
• Ability to identify issues and seek solutions independently.

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state or local protected class.

Job Facts 

• Start Date: Summer 2023
• Length of Assignment: 10 - 12 weeks 
• Location: South San Francisco, CA
• Job Type: Paid Internship