Associate Director, Pathology

Key Skills

Analytical and Problem solving, Data science techniques, Design, Machine learning techniques, SAS

Job Description

The Role

As a Pathologist at Genmab, you will be part of an international Pathology team embedded within Precision Medicine of our Translational & Quantitative Sciences team based in Princeton, New Jersey. In this role you will work with scientists in a state-of-the-art histology and immunohistochemistry laboratory to support a variety of discovery, pre-clinical and clinical programs.

Responsibilities

The anatomic pathologist in this role will impact Genmab’s pipeline from early research to clinical trial stages, providing expertise in histopathological evaluation, tissue-based assay development (IHC, ISH, IF), biomarker strategy and toxicologic pathology for a variety of antibody therapeutics. Scientific curiosity, strategic thinking, and the capacity to work well in cross-functional teams are important traits of the successful candidate.

You will contribute your pathology expertise by both traditional slide evaluation, and by guiding the development and interpretation of advanced tissue-based assays, such as multiplex immunofluorescence panels, digital image analysis, and machine learning image projects.

Your responsibilities include but are not limited to the following:

• Help laboratory personnel in our US and European locations to design and develop immunohistochemistry assays for single-plex chromogenic and fluorescence, in situ hybridization (ISH) assays, multiplex IF and ISH-IF combinations (10% lab work IHC/IF assay development).

• Support our digital pathology team and work closely with Data Sciences to develop and verify digital image analysis algorithms and results from image analysis projects.

• Evaluate, qualitatively and quantitatively (H-Scores, % staining, etc) a variety of immunohistochemical stains for target screening and biomarker assessment.

• Serve as in-house expert representing Genmab in interactions with CROs developing IHC and ISH assays to support our pre-clinical and clinical biomarker programs.

• Perform, as needed, primary reads and/or peer review of pre-clinical toxicology studies, including tissue cross reactivity studies, investigative and GLP studies.

• Provide internal expertise to understand the mechanisms of toxicity observed non-clinically or clinically in order to help design mitigation strategies and minimize risk to patients.

• Contribute with evaluation, and implementation of new technologies and techniques for tissue-based assays and digital image analysis applications.

Requirements

• Doctor in Veterinary Medicine or equivalent degree, with a minimum of 2-5 years of industry experience supporting discovery and development organizations.

• Diplomate, American College of Veterinary Pathologists (or equivalent) in anatomic pathology.

• Graduate degree (Master’s or PhD) desired.

• Solid experience with design and interpretation of immunohistochemistry assays and digital pathology applications.

• Strategic thinking, innovative and collaborative mindset and a willingness to work in multidisciplinary teams.

• Basic knowledge of statistics and data visualization software (SAS, GraphPad, Spotfire).

• Experience managing pathology laboratories desired, but not required.

• Background in immunology and immuno-oncology, knowledge of biomarker development and companion diagnostic development is desired but not required.

For US based candidates, the proposed salary band for this position is as follows:

$142,500.00---$237,500.00

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as bonuses.

About You

• You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
• You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with diverse backgrounds
• You are determined to do and be your best and take pride in enabling the best work of others on the team
• You are not afraid to grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so

Locations

Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you’re in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Genmab is an international biotechnology company with a core purpose guiding its unstoppable team to strive towards improving the lives of patients through innovative and differentiated antibody therapeutics. For more than 20 years, its passionate, innovative and collaborative team has invented next-generation antibody technology platforms and leveraged translational research and data sciences, which has resulted in a proprietary pipeline including bispecific T-cell engagers, next-generation immune checkpoint modulators, effector function enhanced antibodies and antibody-drug conjugates. To help develop and deliver novel antibody therapies to patients, Genmab has formed 20+ strategic partnerships with biotechnology and pharmaceutical companies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO™) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with locations in Utrecht, the Netherlands, Princeton, New Jersey, U.S. and Tokyo, Japan.

Our commitment to diversity, equity, and inclusion

We are committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information. Learn more about our commitments on our website.

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website https://www.genmab.com/privacy.

Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.