Senior Research Associate, Discovery Data Science

Key Skills

Aartificial intelligence, AWS, Bioinformatics, Data Analysis, Data science techniques, Effective communication skills, Git, Machine learning techniques, MLflow, MLOps tools, NumPy, Pandas, Python Programming, Scikit-learn, seaborn

Job Description

The role

Genmab is currently seeking a Senior Research Associate based in the Discovery Data Science department based in Utrecht or Copenhagen. This is a highly collaborative role between the Data Science and the Discovery research department.

You will work in a multidisciplinary, international team of experienced scientists with deep knowledge of immunology and antibody development, with the goal of bringing new, groundbreaking antibody therapeutics to the clinic. We leverage state-of-the-art protein characterization assays and advanced data analysis methods to help improve our therapeutics. Dry- and wet-lab researchers collaborate towards defining project questions, discussing methodology, designing experiments, assessing results, modelling data, and validating predictions. Projects involve computational sequence- and structure-based protein and antibody engineering,

Genmab places a high value on new, transformational data-science approaches to enhance our drug discovery and development efforts. As a Senior Research Associate in the Discovery Data Science department, you will make an impact on the development of ground-breaking new medicines to serve cancer patients with unmet medical needs. In addition, as a fully integrated biotech company, Genmab will give you the chance to experience drug development from discovery to translation into the clinic.

Responsibilities

• You will work closely with data scientists and wet-lab scientists to curate and analyze experimental data related to antibody developability.

• You will conduct exploratory data analysis and statistical analyses.

• You will feed ideas and analyses into the design of new experiments.

• You will train machine-learning models, experimenting with methods, parameters and datasets, to achieve top predictive performance for antibody properties.

• You spar ideas with colleagues and engage in scientific and technical discussions.

• You are well-aware of the biological context of projects and can provide biological interpretations of your results to teams with diverse scientific backgrounds.

• You have excellent communication and collaboration skills to productively contribute to large, multidisciplinary projects in a multicultural team, all while valuing positive attitude and well-being in the workplace.

• You are responsible for the visualization of complex results, turning highly technical concepts into intuitive explanations that can be presented to a diverse scientific audience.

Requirements

• You hold a MSc in the field of computer science, computational biology, biophysics, machine learning, artificial intelligence, bioinformatics or related fields. Alternatively, you hold a BSc with 2 years more of relevant work experience.

• You have 3-5 years' experience in a comparable role, preferable in industry.

• You code proficiently in Python (pandas, numpy, seaborn, scikit-learn).

• You have a good understanding of statistics and basic machine-learning principles.

• You have a solid grasp on molecular biology and protein science.

• You are familiar with version control system such as Git.

• You are an enthusiastic, creative, goal orientated, pro-active and out-of-the-box thinker with a strong ability to work independently.

• You are a team player with excellent interpersonal and communication skills with great command of English, written and spoken. Dutch or Danish not required.

• You are able to work 32-40 hours/week (37 for Denmark) and approx. 2-3 days per week at our offices in Utrecht or Copenhagen.

Nice-to-haves:

• Understanding of antibody biology.

• Proficient in molecular modelling, protein structure prediction, and computational methods for structural analysis. Experience with software such as Rosetta, PyMOL, or similar tools.

• You are familiar with popular geometric deep learning architectures.

• Experience with MLOps platforms, such as MLflow.

• You published in reputable peer-reviewed journals.

• Working knowledge of cloud computing environments such as Databricks or AWS.

About You

• You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
• You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
• You are a generous collaborator who can work in teams with diverse backgrounds
• You are determined to do and be your best and take pride in enabling the best work of others on the team
• You are not afraid to grapple with the unknown and be innovative
• You have experience working in a fast-growing, dynamic company (or a strong desire to)
• You work hard and are not afraid to have a little fun while you do so

Locations

Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you’re in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Founded in 1999 in Copenhagen, Denmark, Genmab is an innovative biotech company that has become a leader in antibody biology and innovation. Our product pipeline and next-generation antibody technologies are the result of our strong company culture, a deep passion for innovation, and desire to transform cancer treatment and serious diseases.

When you work with us, you’ll be part of a warm, fun, dynamic community, and team up with some of the best, most authentic individuals in locations around the world, who care deeply and share in a relentless drive to innovate and create transformational medicines. People who are candid, impact-driven, and a little unconventional; who seek out and embrace the opportunity to build new and bold futures within a rapidly growing and innovative biotech company; who bring their full selves to work and show up for each other - rolling up their sleeves to get the job done. This translates into a place where you can be authentically you; are empowered to innovate, build solutions, and execute; feel cared for and supported in growth; and are a critical part of changing the lives of patients around the world through transformative cancer treatment.

Our commitment to diversity, equity, and inclusion

We are committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information. Learn more about our commitments on our website.

Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website https://www.genmab.com/privacy.

Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.