Sr. Director, Head of Translational Medicine - Oncology

Key Skills

Drug Discovery, Effective communication skills, High performance computing- HPC, Machine learning techniques, Planning and organization

Job Description

Your primary duties will be to

• Play a key strategic role in integration of the patient perspective to inform disease modeling and drug discovery efforts, including understanding the standard of care, areas of unmet need, and identifying viable target-patient profiles. 
• Partner with colleagues in data science & machine learning (DSML) and in corporate development to identify critical data assets and/or commission the generation of data for discovery efforts in oncology. 
• Collaborate closely with data science & machine learning (DSML) colleagues to define machine learning (ML) models for clinical data to inform our understanding of patient trajectory and patient subpopulations and to identify novel endpoints for clinical trials.
• Assist drug discovery teams to prepare IND-enabling data packages in alignment with clinical development objectives.
• Longer-term, partner with market planning and commercial development colleagues on market research and target-patient profiles for new programs.
• Contribute as a clinical area expert dedicated to translational approaches and early clinical development.
• Participate in efforts to model and design ML-enabled clinical trials for internal and/or partnered programs. 
• Participate in strategic overview of presentations, publications, and internal/ external communications along with accountable project and program leadership.

You will be joining as the founding team of a biotech startup that has long-term stability due to significant funding, but yet is very much in formation. A lot can change in this early and exciting phase, providing many opportunities for significant impact. You will work closely with a very versatile team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us, and help make a difference to patients!

About You

• MD or MD/PhD in a technical field (oncology, immuno-oncology, cell & molecular biology, etc.) or equivalent, with 8+ years of postdoctoral experience.
• Experience working with cancer patients, patient data, patient trajectories/disease progression and clinical trial design. 
• Experience with biomarker data sets such as; clinical imaging, proteomics, metabolomics, and transcriptomics.
• Familiarity with pioneering oncology translational models (patient-derived organoids, patient derived xenografts, primary metastatic etc)
• Experience working as part of a high-performance team, including goal setting and contributing to a culture of effective, high-quality methods development and reducing those methods to a practical implementation.
• Excellent teamwork, communication, time management and organization skills
• Strong verbal and written communication skills across all levels both within an organization and with external partners.

Compensation & Benefits at insitro

Our target starting salary for successful US-based applicants for this role is $250,000 - $290,000. To determine starting pay, we consider multiple job-related factors including a candidate’s skills, education and experience, market demand, business needs, and internal parity. We may also adjust this range in the future based on market data. 

This role is eligible for participation in our Annual Performance Bonus Plan (based on company targets by role level and annual company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies.

In addition, insitro also provides our employees:

• 401(k) plan with employer matching for contributions
• Excellent medical, dental, and vision coverage (insitro pays 100% of premiums for employees), as well as mental health and well-being support
• Open, flexible vacation policy
• Paid parental leave
• Quarterly budget for books and online courses for self-development
• Support to occasionally attend professional conferences that are meaningful to your career growth and development
• New hire stipend for home office setup
• Monthly cell phone & internet stipend
• Access to free onsite baristas and cafe with daily lunch and breakfast
• Access to free onsite fitness center
• Commuter benefits