Post Doc - Data Sciences Process Modeling

Key Skills

Python Programming, SQL, AWS, Big Data Technology, Scala Programming, Aartificial intelligence, Data science techniques, MATLAB Programming, NoSQL, Data Analytics, R Programming

Job Description

The Data Sciences team at Sanofi is working to accelerate the development and optimization of biologics purification processes using computational tools and high-throughput experimental workflows. Traditional modeling approaches for process development involve either rigorous first principles models which are time consuming to design and calibrate, or empirical design of experiments (DoE) approaches which provide little fundamental understanding of a system.

We are looking for a highly motivated post-doctoral scientist to develop new and innovative hybrid models which combine the best characteristics of both mechanistic and empirical models to accelerate process development, optimization, and troubleshooting. This role will help design a novel simulation framework that can be used to model downstream unit operations such as chromatography and filtration using a combination of physics-based and empirical (MVA/ML) techniques. Additionally, the scientist will help develop a standardized model calibration workflow, leveraging high-throughput experimentation to rapidly generate data for model development. This high-impact project will be a key step in Sanofi’s digital transformation to accelerate bringing medicines to patients.

Basic Qualifications:

• Ph.D. + 0-3 years of postdoctoral training in engineering, mathematics, or related field
• All candidates must have permanent U.S. work authorization. No visa sponsorship will be provided
• Experience solving ODE/PDE systems as well as implementing model calibration and optimization approaches
• Strong programming skills in scientific languages such as MATLAB, R, or Python
• Experience using empirical modeling techniques including but not limited to statistics, multivariate analysis, machine learning
• Ability to derive models of physical systems based on conservation laws

Preferred Qualifications:

• Experience with downstream bioprocessing unit operations (chromatography, filtration, etc.)
• Experience developing hybrid models
• Strong publication background

At Sanofi R&D North America, we deliver meaningful solutions for patients. We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce – and workplace – which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society.

As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. This position will require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.