Bioinformatics Scientist, R&D

Key Skills

Python Programming, Scala Programming, C++, Java Programming, Machine learning techniques, Data science techniques, SQL, Apache Hadoop, MapReduce, TensorFlow, PyTorch, R Programming, AWS

Job Description

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals. With revenues of more than $24 billion and the largest investment in R&D in the industry, we give our people the resources and opportunities to make significant contributions to the world.

Location/Division Specific Information

The position is based in Austin, TX and is part of the extended Bioinformatics team within the Clinical Next Generation Sequencing Division (CSD). The mission of this business unit is to develop next-generation sequencing based solutions to support research and IVD applications in oncology and other clinical domains.

How will you make an impact?

Next Generation Sequencing (NGS) is rapidly reshaping life sciences, translational research, and clinical diagnostics. At Thermo Fisher Scientific, a leading contributor in these fields, we are dedicated to broaden the range of NGS applications with a focus on comprehensive oncology diagnostics. If you are a motivated and innovative bioinformatics scientist seeking to advance your expertise in these fields, we would like to invite you to join our NGS R&D Bioinformatics team.

What will you do??

You will:

• provide complex and custom bioinformatics analysis to support development of targeted sequencing assays.
• guide molecular biologists with data interpretation and analysis such as variant calling, CNV detection, RNA fusion detection and genome annotations.
• support new NGS product introductions (NPI) and lead data analysis efforts for validation studies to be submitted to FDA for regulatory approvals.
• work in close collaboration with other bioinformatics, software, molecular biology, quality, instrument, and product management teams, both at Austin and at remote sites.
• apply innovative data science approaches to troubleshoot and improve NGS assay performance.
• work independently, prioritizing, multi-tasking, and applying data analysis and problem-solving expertise to develop and improve products targeting important areas of unmet medical need.

How will you get here?

Education and Experience

• A master's graduate degree in bioinformatics, statistics, mathematics, computer science or a related field required. PhD in bioinformatics, statistics, mathematics, computer science or a related field preferred.
• You should have a solid knowledge of the next-generation sequencing analysis, background in statistics, understanding of data analysis principles as demonstrated by your publication history or industry experience.
• Proficiency in Python or Perl, R, Linux shell scripting and scientific data visualization is required.
• Experience with public cancer genomic data sources such as TCGA, COSMIC, ClinVar is preferred.
• In depth understanding of genomics and molecular biology will make you a stronger candidate.
• Experience with PCR primer design, molecular barcoding, sequence analysis is particularly welcome.
• Effective communication skills, especially for presenting scientific results, keeping records and working collaboratively in a team of scientists are necessary.
• Direct experience with product development cycles and IVD regulations is a plus.

At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission—enabling our customers to make the world healthier, cleaner and safer.