Bioinformatics Software Engineer

Key Skills

Python Programming, Scala Programming, C++, Java Programming, Machine learning techniques, Data science techniques, SQL, Apache Hadoop, MapReduce, TensorFlow, PyTorch, R Programming, AWS

Job Description

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $25 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them.

Location / Division

West Hills, CA or Remote U.S. / Transplant Diagnostics

How will you make an impact?

This is a key position in the Bioinformatics group within the Transplant Diagnostics R&D IS team. The successful candidate will have the opportunity to partner with lab scientists, data analysts, software engineers and domain experts to build cutting-edge technologies and develop innovative molecular typing and antibody detection products.

The successful candidate will develop, improve, and maintain tools, pipelines, and software for the analysis of complex HLA typing data from PCR, microarray, NGS, and antibody detection platforms. This role will work in collaboration with the research staff and other departments, and requires knowledge of data analysis methods, software development, bioinformatics, statistics, molecular biology, as well as the ability to quickly grasp new disciplines.

What will you do?

• Build software tools, including development and implementation of new computational algorithms, machine learning and statistical models to provide solutions for process automation and data analytics for the R&D and manufacturing teams
• Develop pipelines for NGS analysis and other bioinformatics workflows
• Build and maintain an internal Bioinformatics web portal for communication and distribution of Bioinformatics tools throughout the Transplant Diagnostics division
• Search relevant sequence information from external sources for primer and probe design, as well as data mining of genomic libraries and genomes
• Analyze and interpret complex experimental results and work hand in hand with lab scientists for the research and development of new molecular and antibody products
• Collect, clean and manage data from various sources, including Excel spreadsheets, text files and SQL databases
• Actively participate in software code and design reviews
• Regularly communicate accomplishments and progress to team members and management
• Develop, modify and execute software test plans and test cases for data analysis software
• Create and validate technical specifications for customer-facing product documentation
• Interact with Research, Production, software, and IT staff. May interact with customer support at times

How will you get here?

Education / Experience

• PhD from an accredited higher learning institution with studies in Computer Science, Bioinformatics, Computation Biology, Life Sciences/Molecular Biology or related field AND 2 years of related postdoctoral or industrial experience; OR master’s degree in Computer Science, Bioinformatics, Computational Biology, Life Sciences/Molecular Biology or related field AND 4 years of related work experience; OR bachelor’s degree in Computer Science, Bioinformatics, Computational Biology, Life Sciences/Molecular Biology or related field AND 6 years of related work experience
• Experience developing analytical software tools utilizing programming languages, such as C#, Python, R, JavaScript, and SQL
• Experience with relational databases
• Experience in developing web tools and services
• Experience with cloud technologies such as AWS and docker

Knowledge, Skills, Abilities

• Proficiency in building and maintaining NGS or other bioinformatics analysis pipelines
• Proficiency working in Windows and Linux environments
• Pragmatic self-starter who is proactive, self-motivated, team-oriented, and customer-focused with a strong work ethic
• Ability to meet deadlines within a dynamic environment and able to manage multiple tasks simultaneously while adapting to changing priorities
• Be curious, detail oriented, and analytical, with a proven ability to learn quickly
• Sound understanding of statistics, machine learning algorithms, the ability to generate robust predictive models for multidimensional data
• Understanding wet lab techniques and principles in the field of Molecular Biology, Genomics, and/or Biochemistry
• Willingness to thoroughly understand products and new projects and to stay current with Bioinformatics, computational or industry trends
• Good verbal and written communication and well-founded problem-solving skills
• Demonstrated skills in project management and formal continuous process improvement techniques
• Ability to work effectively in collaboration with diverse groups of people

This role requires occasional travel to the West Hills, CA site.

Preferred Qualifications

• Knowledge in immunology
• Experience in formal verification of software or system in a regulated environment (ex. medical device etc.)
• Experience administrating a Linux system

Our global team of more than 75,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services and Patheon.