Postdoctoral Computational Biologist/Research Associate (Fixed Term)

University of Cambridge
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Job Description

We are seeking a Post-doctoral Computational Biologist to apply novel machine learning and artificial intelligence approaches to existing as well as newly generated multi-omics datasets.

PROJECT: Inflammatory Bowel Diseases (IBD) such as Crohn's Disease (CD) and Ulcerative Colitis (UC) cause chronic, relapsing inflammation of the intestine. In the absence of a cure, patients suffer a lifetime of debilitating symptoms. This project aims to develop and apply novel computational methods to existing and newly generated molecular multimodal datasets derived from primary human tissue samples as well as patient-derived intestinal organoids. As part of a large multi-disciplinary team the candidate will develop molecular disease classifiers and clinical biomarkers as well as identify novel treatment targets. The latter will then be tested on our patient-derived organoid models to identify the most promising candidates for further development into novel treatments.

CANDIDATE: Applicants should have completed a PhD in a relevant subject for example applied mathematics, computer science, genetics, or molecular biology. The ideal candidate will have a strong background in, and exceptional enthusiasm for, computational biology and machine learning, as well as a strong interest in the underlying biological/disease processes and a passion for data driven science. We are looking for a highly motivated and enthusiastic individual capable of thinking and working independently, and as part of a multi-disciplinary team.

ENVIRONMENT: The post-holder will join a diverse, supportive, and friendly team of scientists, clinicians, and other professionals based at the Wellcome-MRC Cambridge Stem Cell Institute (CSCI) and the Department of Paediatrics, University of Cambridge. This project is a close collaboration between the groups of Dr Matthias Zilbauer (CSCI) and Dr Namshik Han (Milner Therapeutics Institute (MTI)). The post-holder will therefore be part of the MTI computational research group led by Dr Namshik Han. The CSCI and the MTI are both located in the Jeffrey Cheah Biomedical Centre, based at the heart of the Cambridge Biomedical Research Campus providing access to state-of-the-art research facilities.

Personal development: Our aim is to provide a supportive and inspiring work environment that enables each individual team member to thrive and reach their maximum potential. In addition to a wide range of professional development opportunities offered by CSCI and University of Cambridge, the post-holder will be encouraged (and financially supported) to present their work at national and international meetings. The development of a collaborative network and participation in relevant trainings courses is highly encouraged. Further information on opportunities for post-doctoral researchers including college the Postoc Careers Service and the CSCI Postdoc Mentoring Scheme can be found here:

FUNDING: Funding is available for 3 years in the first instance. The successful candidate will be encouraged and supported to obtain external personal fellowship and grant support.

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Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

The closing date for applications is: 28th May 2023

The interview date for the role is: TBC

Please quote reference PS36282 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Company Info.

University of Cambridge

The University of Cambridge is a public collegiate research university in Cambridge, United Kingdom. Founded in 1209 and granted a royal charter by Henry III in 1231, Cambridge is the world's third oldest surviving university and one of its most prestigious, currently ranked second best in the world and the best in Europe by QS World University Rankings.

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