Principal Bioinformatics Software Engineer, Clinical Pipeline

Key Skills

Agile methodologies, Java Programming, Linux Operating system, Python Programming, R Programming, SQL

Job Description

6000! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.

NIBR Oncology is seeking an experienced software engineer with domain knowledge in bioinformatics to help develop applications to marshal, transform and visualize complex data sets from the clinical research space, such as genotypic and other omics biomarker assay outputs. While exciting, this sometimes presents a challenge—and we want you to help! Specifically, in this hands-on role, you will collaboratively architect and design software solutions that accelerate the work of our data scientists and lead or contribute to efforts to enhance and improve existing systems. You will work within a larger Engineering team following Agile practices and collaborate closely with data scientists to deliver the most impactful solutions possible. You should have a strong software engineering background and an understanding of the scientific domain.

RESPONSIBILITIES

• Design and build performant, well tested NGS production data processing pipelines (scRNA, bulk RNA, targeted DnaSeq, etc.)
• Contribute to joint development efforts with data scientists on tooling to filter and QC genomic variant calls
• Work on early-stage data analysis for new assays or novel data types
• Lead and manage development efforts, define project roadmaps, handle production support requests
• May manage, coach and mentor a junior developer

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

• A minimum 5 years of experience working in bioinformatics software engineering
• A BS Degree
• Experience working with clinical omics data in a regulated production environment strongly preferred (CLIA, CAP)
• Experience in Python development required
• Experience with R, Java and SQL are preferred
• Proficiency in a Linux environment is required
• Previous experience with HPC clusters is preferred
• Practical knowledge of software engineering, Agile development methodologies and development operations best practices is required
• Experience working collaboratively with a cross-functional team of engineers and data scientists is required

Why Novartis?

766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!